ClonalFrame

inference of bacterial microevolution using multilocus sequence data

Install

All systems
curl cmd.cat/ClonalFrame.sh
Debian Debian
apt-get install clonalframe
Ubuntu
apt-get install clonalframe
image/svg+xml Kali Linux
apt-get install clonalframe
Windows (WSL2)
sudo apt-get update sudo apt-get install clonalframe
Raspbian
apt-get install clonalframe

clonalframe

inference of bacterial microevolution using multilocus sequence data

ClonalFrame identifies the clonal relationships between the members of a sample, while also estimating the chromosomal position of homologous recombination events that have disrupted the clonal inheritance. ClonalFrame can be applied to any kind of sequence data, from a single fragment of DNA to whole genomes. It is well suited for the analysis of MLST data, where 7 gene fragments have been sequenced, but becomes progressively more powerful as the sequenced regions increase in length and number up to whole genomes. However, it requires the sequences to be aligned. If you have genomic data that is not aligned, it is recommend to use Mauve which produces alignment of whole bacterial genomes in exactly the format required for analysis with ClonalFrame.