arden-create
specificity control for read alignments using an artificial reference
Install
- All systems
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curl cmd.cat/arden-create.sh
- Debian
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apt-get install arden - Ubuntu
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apt-get install arden - Kali Linux
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apt-get install arden - Windows (WSL2)
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sudo apt-get updatesudo apt-get install arden - Raspbian
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apt-get install arden - Dockerfile
- dockerfile.run/arden-create
arden
specificity control for read alignments using an artificial reference
ARDEN (Artificial Reference Driven Estimation of false positives in NGS data) is a novel benchmark that estimates error rates based on real experimental reads and an additionally generated artificial reference genome. It allows the computation of error rates specifically for a dataset and the construction of a ROC-curve. Thereby, it can be used to optimize parameters for read mappers, to select read mappers for a specific problem or also to filter alignments based on quality estimation.