melting
compute the melting temperature of nucleic acid duplex
Install
- All systems
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curl cmd.cat/melting.sh
- Debian
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apt-get install melting - Ubuntu
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apt-get install melting - Kali Linux
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apt-get install melting - Windows (WSL2)
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sudo apt-get updatesudo apt-get install melting - Raspbian
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apt-get install melting - Dockerfile
- dockerfile.run/melting
melting
compute the melting temperature of nucleic acid duplex
This program computes, for a nucleic acid duplex, the enthalpy, the entropy and the melting temperature of the helix-coil transitions. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program first computes the hybridisation enthalpy and entropy from the elementary parameters of each Crick's pair by the nearest-neighbor method. Then the melting temperature is computed. The set of thermodynamic parameters can be easily changed, for instance following an experimental breakthrough.