minimac4

Fast Imputation Based on State Space Reduction HMM

Install

All systems
curl cmd.cat/minimac4.sh
Debian Debian
apt-get install minimac4
Ubuntu
apt-get install minimac4
image/svg+xml Kali Linux
apt-get install minimac4
Windows (WSL2)
sudo apt-get update sudo apt-get install minimac4
Dockerfile
dockerfile.run/minimac4

minimac4

Fast Imputation Based on State Space Reduction HMM

Minimac4 is a lower memory and more computationally efficient implementation of "minimac2/3". It is an algorithm for genotypic imputation that works on phased genotypes (say from MaCH). Minimac4 is designed to handle very large reference panels in a more computationally efficient way with no loss of accuracy. This algorithm analyzes only the unique sets of haplotypes in small genomic segments, thereby saving on time\-complexity, computational memory but no loss in degree of accuracy.