pal2nal.pl
converts proteins to genomic DNA alignment
Install
- All systems
-
curl cmd.cat/pal2nal.pl.sh
- Debian
-
apt-get install pal2nal - Ubuntu
-
apt-get install pal2nal - Kali Linux
-
apt-get install pal2nal - Windows (WSL2)
-
sudo apt-get updatesudo apt-get install pal2nal - Dockerfile
- dockerfile.run/pal2nal.pl
pal2nal
converts proteins to genomic DNA alignment
PAL2NAL is a program that converts a multiple sequence alignment of proteins and the corresponding DNA (or mRNA) sequences into a codon-based DNA alignment. The program automatically assigns the corresponding codon sequence even if the input DNA sequence has mismatches with the input protein sequence, or contains UTRs, polyA tails. It can also deal with frame shifts in the input alignment, which is suitable for the analysis of pseudogenes. The resulting codon-based DNA alignment can further be subjected to the calculation of synonymous (Ks) and non-synonymous (Ka) substitution rates.