prof

secondary structure and solvent accessibility predictor

Install

All systems
curl cmd.cat/prof.sh
Debian Debian
apt-get install profphd
Ubuntu
apt-get install profphd
image/svg+xml Kali Linux
apt-get install profphd
Windows (WSL2)
sudo apt-get update sudo apt-get install profphd
Raspbian
apt-get install profphd

profphd

secondary structure and solvent accessibility predictor

This package provides prof(1), the protein secondary structure, accessibility and transmembrane helix predictor from Burkhard Rost. Prediction is either done from protein sequence alone or from an alignment - the latter should be used for optimal performance. How well does prof(1) perform? * Secondary structure is predicted at an expected average accuracy > 72% for the three states helix, strand and loop. * Solvent accessibility is predicted at a correlation coefficient (correlation between experimentally observed and predicted relative solvent accessibility) of 0.54 * Transmembrane helix prediction has an expected per-residue accuracy of about 95%. The number of false positives, i.e., transmembrane helices predicted in globular proteins, is about 2%.