pscan_chip

ChIP-based identifcation of TF binding sites

Install

All systems
curl cmd.cat/pscan_chip.sh
Debian Debian
apt-get install pscan-chip
Ubuntu
apt-get install pscan-chip
image/svg+xml Kali Linux
apt-get install pscan-chip
Windows (WSL2)
sudo apt-get update sudo apt-get install pscan-chip

pscan-chip

ChIP-based identifcation of TF binding sites

The regions on genomic DNA juxtaposed to regions that code for RNA or protein are known to feature many short regions to which proteins bind that are a requirement for the gene to be read out. These so called transcription factors (TFs) are proteins themselves and their abundance is dependent on yet other TFs. Much of the cellular differentiation to have different tissues and the dynamic molecular responses to stimuli are controlled transcriptionally. The identification of the exact oligonucleotides to which TF may be binding are described statistically by an observed enrichment of motifs of such TF binding sites by software like pscan. This tool further constraints the search with data from ChIP-Seq experiments from which the regions of DNA that is covered by a TF may be described.