psiblast_res_to_fasta_dbpairwise

predicts if a substitution in a protein has a phenotypic effect

Install

All systems
curl cmd.cat/psiblast_res_to_fasta_dbpairwise.sh
Ubuntu
apt-get install sift
image/svg+xml Kali Linux
apt-get install sift
Windows (WSL2)
sudo apt-get update sudo apt-get install sift
OS X
brew install sift
Dockerfile
dockerfile.run/psiblast_res_to_fasta_dbpairwise

sift

predicts if a substitution in a protein has a phenotypic effect

SIFT is a sequence homology-based tool that sorts intolerant from tolerant amino acid substitutions and predicts whether an amino acid substitution in a protein will have a phenotypic effect. SIFT is based on the premise that protein evolution is correlated with protein function. Positions important for function should be conserved in an alignment of the protein family, whereas unimportant positions should appear diverse in an alignment.