run-gen-ref
Burrows-Wheeler Aligner
Install
- All systems
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curl cmd.cat/run-gen-ref.sh
- Debian
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apt-get install bwa - Ubuntu
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apt-get install bwa - Kali Linux
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apt-get install bwa - Fedora
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dnf install bwa - Windows (WSL2)
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sudo apt-get updatesudo apt-get install bwa - OS X
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brew install bwa - Raspbian
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apt-get install bwa - Dockerfile
- dockerfile.run/run-gen-ref
bwa
Burrows-Wheeler Aligner
BWA is a software package for mapping low-divergent sequences against a large reference genome, such as the human genome. It consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. The first algorithm is designed for Illumina sequence reads up to 100bp, while the rest two for longer sequences ranged from 70bp to 1Mbp. BWA-MEM and BWA-SW share similar features such as long-read support and split alignment, but BWA-MEM, which is the latest, is generally recommended for high-quality queries as it is faster and more accurate. BWA-MEM also has better performance than BWA-backtrack for 70-100bp Illumina reads.