smarteigenstrat
reduction of population bias for genetic analyses
Install
- All systems
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curl cmd.cat/smarteigenstrat.sh
- Debian
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apt-get install eigensoft - Ubuntu
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apt-get install eigensoft - Kali Linux
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apt-get install eigensoft - Windows (WSL2)
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sudo apt-get updatesudo apt-get install eigensoft - Raspbian
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apt-get install eigensoft - Dockerfile
- dockerfile.run/smarteigenstrat
eigensoft
reduction of population bias for genetic analyses
The EIGENSOFT package combines functionality from the group's population genetics methods (Patterson et al. 2006) and their EIGENSTRAT stratification method (Price et al. 2006). The EIGENSTRAT method uses principal components analysis to explicitly model ancestry differences between cases and controls along continuous axes of variation; the resulting correction is specific to a candidate marker's variation in frequency across ancestral populations, minimizing spurious associations while maximizing power to detect true associations. The EIGENSOFT package has a built-in plotting script and supports multiple file formats and quantitative phenotypes.