t_coffee

Multiple Sequence Alignment

Install

All systems
curl cmd.cat/t_coffee.sh
Debian Debian
apt-get install t-coffee
Ubuntu
apt-get install t-coffee
image/svg+xml Kali Linux
apt-get install t-coffee
Windows (WSL2)
sudo apt-get update sudo apt-get install t-coffee
Raspbian
apt-get install t-coffee

t-coffee

Multiple Sequence Alignment

T-Coffee is a multiple sequence alignment package. Given a set of sequences (Proteins or DNA), T-Coffee generates a multiple sequence alignment. Version 2.00 and higher can mix sequences and structures. T-Coffee allows the combination of a collection of multiple/pairwise, global or local alignments into a single model. It can also estimate the level of consistency of each position within the new alignment with the rest of the alignments. See the pre-print for more information T-Coffee has a special called M-Coffee that makes it possible to combine the output of many multiple sequence alignment packages. In its published version, it uses MUSCLE, PROBCONS, POA, DiAlign-TS, MAFFT, Clustal W, PCMA and T-Coffee. A special version has been made for Debian, DM-Coffee, that uses only free software by replacing Clustal W by Kalign. Using the 8 Methods of M-Coffee can sometimes be a bit heavy. You can use a subset of your favorite methods if you prefer.